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Arthur Saltzman, BA, MSResearch Scientist Nathan S. Kline Institute for Psychiatric Research Histology Facility Arthur.Saltzman@nki.rfmh.org P: (845)398-5565 F: (845)398-5422 |
Education
BA (Biology) SUNY Oswego, Oswego, NYMA (Liberal Studies) New York University, New York, NY
Research Interests
The main goal of research is to understand the molecular and cellular substrates that regulate selective vulnerability of neurons to degeneration. A multidisciplinary approach of state-of-the-art functional genomics, including microaspiration of select neuronal types through laser capture microdissection and single population RNA-sequencing along with regional proteomics approaches combined with immunohistochemical and cell biological techniques is utilized as part of the experimental design. Particular emphasis is placed upon analyzing the interactomes of individual neuronal populations as a means of understanding the complex cascade of cellular events that occurs under pathologic conditions such as aging, Alzheimer’s disease (AD), Down syndrome (DS), and mild cognitive impairment (MCI) as well as animal and cellular models of neurodegenerative disorders.