Publications for Monkia Pawlik, PhD

Requests for papers can be made by emailing Monkia Pawlik.

Publications

  1. Kaur G, Sharma A, Xu W, Gerum S, Alldred MJ, Subbanna S, Basavarajappa BS, Pawlik M, Ohno M, Ginsberg SD, Wilson DA, Guilfoyle DN, Levy E.Glutamatergic transmission aberration: a major cause of behavioral deficits in a murine model of Down's syndrome. J Neurosci, 2014;34(15):5099-106. PMCID: PMC3983795 [Available on 10/9/2014] Click for abstract

  2. Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson DW, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, Westaway D, Mathews PM, Levy E, Cuervo AM, Nixon RA. Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis. Autophagy. 2011 Jul 1;7(7) PMID: 21464620 PMCID:PMC3359468 HTML PDF
  3. Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson DW, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, Westaway D, Mathews PM, Levy E, Cuervo AM, Nixon RA. Reversal of autophagy Dysfunction in the TgCRND8 mouse model of Alzheimer’s Disease ameliorates amyloid pathologies and memory deficits, 2011, Brain 134, 1, 258-277. PMCID: PMC3009842 HTML PDF
  4. Kaur G, Mohan P, Pawlik M, DeRosa S, Fajiculay J, Che S, Grubb A, Ginsberg SD, Nixon RA, Levy E. Cystatin C Rescues Degenerating Neurons in a Cystatin B- Knockout Mouse Model of Progressive Myoclonus Epilepsy, 2010, Am J Pathol. 177, 5, 2256-2267. PMID:20889561 / PMCID:PMC2966785 HTML PDF
  5. Tizon B, Sahoo S, Yu H, Gauthier S, Kumar AR, Mohan P, Figliola M, Pawlik M , Grubb A, Uchiyama Y, Bandyopadhyay U, Cuervo AM, Nixon RA, Levy. EInduction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines, 2010, PLoS One 23;5(3):e9819. HTML PDF
  6. Yang DS, Kumar A, Stavrides P, Peterson J, Peterhoff CM, Pawlik M, Levy E, Cataldo AM, Nixon RA. Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer’s Disease, 2008, The American Journal of Pathology 173, 3, 665-681. HTML PDF
  7. Weiqian Mi, Monika Pawlik, Magdalena Sastre, Sonia Jung, David Radvinsky, Andrew M. Klein, John Sommer, Mathias Staufenbiel, Stephen D. Schmidt, Ralph A. Nixon, Paul M. Mathews and Efrat Levy, Cystatin C Inhibits Amyloid b Deposition in Alzheimer’s Disease Mouse Models, 2007 Nature Genetics 39, 12, 1440-1442. PMID: 18026100 Click for abstract
  8. Monika Pawlik, Deborah A.C. Otero, Minkyu Park, Wolfgang H. Fischer, Efrat Levy and Tsunao Saitoh, Proteins that Bind to the RERMS Region of b Amyloid Precursor Protein, 2007, Biochemical and Biophysical Research Communications 355, 907-912. HTML PDF
  9. Weiqian Mi, Huang Yu, Monika Pawlik and Efrat Levy. Cystatin C Binds Soluble Amyloid b in Vivo Inhibiting Amyloid b, Oligomerization and Fibril Formation, 2006, Alzheimer’s Disease and Dementia 2,3, P. S610
  10. Efrat Levy, Weiqian Mi, Belen Tizon, David Radvinsky, Andrew M. Klein, John Sommer, Paul M. Mathews, Stephen D. Schmidt, Ralph A. Nixon and Monika Pawlik, Cystatin C Overexpression Inhibits Amyloid b Accumulation and Deposition in APP Transgenic Mice, 2006, Alzheimer’s Disease and Dementia 2,3, P. S35
  11. Magdalena Sastre, Miguel Calero, Monika Pawlik, Paul Mathews, Ashok Kumar, Vlatko Danilov, Stephen D. Schmidt, Ralph A. Nixon, Blas Frangione and Efrat Levy. Binding of Cystatin C to Alzheimer's Amyloid b Inhibits in Vitro Amyloid Fibril Formation, 2004, Neurobiology of Aging 25, pp.1033-1043. PMID: 15212828. Click for abstract
  12. Monika Pawlik, Magdalena Sastre, Miguel Calero, Paul Mathews, Stephen D. Schmidt, Ralph A. Nixon and Efrat Levy, Overexpression of Human Cystatin C in Transgenic Mice does not Affect Endogenous Amyloidß Production, 2004, Journal of Molecular Neuroscience 22, 1-2, pp.13-18. PMID: 14742906. Click for abstract
  13. Monika Pawlik, Vlatko Danilov, Katerina Mancevska, Michaela Morbin, Fabrizio Tagliavini and Efrat Levy, Hemorrhages Caused by
    Overexpression of Cystatin C in Transgenic Mice, 2002, Neurobiology of Aging 23, p.S242, Efrat Levy and Monika Pawlik, Cystatin C Transgenic Mice, an Animal Model for Cerebral Hemorrhage 2001, Abstracts of the 31st Annual Meeting of the Society for Neuroscience 27, No. 427.18 [no abstract available]
  14. Miguel Calero, Monika Pawlik, Claudio Soto, Eduardo Castano, Einar M. Sigurdsson, Asok Kumar, Gloria Gallo, Blas Frangione and Efrat Levy, Distinct Properties of Wild-type and the Amyloidogenic Human Cystatin C Variant of Hereditary Cerebral Hemorrhage with Amyloidosis, Icelandic Type, 2001, Journal of Neurochemistry 77, pp. 628-637. PMID: 11299325 Click for abstract
  15. Monika Pawlik, Magdalena Sastre, Asok Kumar, Gloria Gallo, Bernardino Ghetti, Fabrizio Tagliavini and Efrat Levy, Codeposition of Cystatin C with Amyloid–ß-Protein in the Brain of Alzheimer’s Disease Patients, 2000, Neurobiology of Aging 21, p. S194
  16. Miguel Calero, Magdalena Sastre, Monika Pawlik, Blas Frangione and Efrat Levy, Association of Cystatin C with Amyloid-ß-Protein, 2000, Neurobiology of Aging 21, p S118
  17. Monika Pawlik, Eberhard Fuchs, Lary C. Walker and Efrat Levy, Primate-like Amyloid-ß Sequence but Cerebral Amyloidosis in Aged Tree Shrews, 1999, Neurobiology of Aging 20, pp. 47-51. PMID: 10466892. Click for abstract
  18. Monika Pawlik, Eberhard Fuchs, Lary C. Walker and Efrat Levy, No Cerebral Amyloidosis in Aged Tree Shrews with Primate-like Amyloid-ß Sequence, 1999, Abstracts of the 30th Annual Meeting of the Society for Neuroscience 25, No. 1859 [no abstract available]
  19. Hai-Ling Li, Jean-Marc Roch, Monika Pawlik, Sam Sisodia and Tsunao Saitoh, Neurite Extension Assay Detects the defective Function due to Swedish Mutation in Amyloid ß/A4 Protein (APP), 1995, Abstracts of the 26th Annual Meeting of the Society for Neuroscience 21, No 671.3 [no abstract available]
  20. Tsunao Saitoh, , Lee-Way Jin, Jean-Marc Roch and Monika Pawlik, Induction of Signal Transducing Pathways by APP Binding to the Cell Surface Receptor, 1995, Research Advances in Alzheimer’s Disease and Related Disorders, Eds. K.Iqbak, J. Mortimer, B.Weinblad and H. Wisniewski, pp. 693-699 [no abstract available]
  21. Tsuano Saitoh, Lee-Way Jin, Jean-Marc Roch and Monika Pawlik, Induction of Signal Transducing Pathways by APP Binding to the Cell Surface Receptor, 1994, Neurobiology of Aging 15, Supplement 1, No 654.
  22. Torsten May, Hans Rommelspacher and Monika Pawlik, (3H)Harman Binding Experiments. I: A Reversible and Selective Radioligand for Monoamine Oxidase Subtype A in CNS of the Rat, 1991, Journal of Neurochemistry 56, pp.490-49. PMID: 1988552. Click for abstract
  23. Torsten May, Monika Pawlik and Hans Rommelspacher, (3H)Harman Binding Experiments. II: Regional and Subcellular Distribution of Specific (3H)Harman Binding and Monoamine Oxidase Subtype A and B Activity in Marmoset and Rat, 1991, Journal of Neurochemistry 56, pp.500-508. PMID: 1988553. Click for abstract
  24. Torsten May, Monika Pawlik and Ulrike Immendörfer, (3H)Harman Binds Selectively and with High Affinity to Monoamine Oxidase (EC 1.4.3.4) Subtype A in Rat and Marmoset, 1990, Naunyn-Schmiedberg’s Archives of Pharmacology 341, Supplement No. 385
  25. Monika Pawlik, Peter Kaulen, Hans G. Baumgarten and Hans Rommelspacher, Quantitative Autoradiography of (3H)Norharman ((3H)ß-Carboline) Binding Sites in the Rat Brain, 1990, Journal of Neuroanatomy 3, 19-24. PMID: 2156525. Click for abstract
  26. Monika Pawlik and Hans Rommelspacher, Demonstration of a Dinstinct Class of High-Affinity Binding Sites for (3H)Norharman ((3H)ß-Carboline) in the Rat Brain, 1988, European Journal of Pharmacology 147, pp.163-171. PMID: 3366173. Click for abstract
  27. Hans Rommelspacher, Monika Pawlik and Sabine Straub, Are there Specific ß-Carboline Receptors in Rat Brain? 1988, Naunyn-Schmiedberg’s Archives of Pharmacology 337, Supplement No. 461
  28. Monika Pawlik, High Affinity Binding Sites for (3H)Norharman (ß-Carboline) in Rat Brain, 1987, Naunyn-Schmiedberg’s Archives of Pharmacology 337, Supplement No. 38

[last updated 8.27.14]