Publications for Aidong (David) Yuan, PhD

Requests for papers can be made by emailing David.

Original Publications

  1. Yuan A, Kumar A, Sasaki T, Duff K, Nixon RA. Global axonal transport rates are unaltered in Htau mice in vivo. J Alzheimers Dis, 2013, 37(3):579-86. PMID: 23948900 PMC3819434 HTML PDF
  2. Rao MV, Yuan A, Campbell J, Kumar A, Nixon RA. The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament network. PLoS One, 2012;7(9):e44320. Click for abstract PDF
  3. Yuan A, Sasaki T, Kumar S, Peterhoff C, Rao MV, Liem RK, Julien J-P, Nixon RA. Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and PNS axons. J Neurosci, 32(25):8501-8. PMID: 27723690 PMCID:PMC3405552 Click for abstract PDF
  4. Yuan A, Rao MV, Veeranna, Nixon RA. Neurofilaments at a glance. J Cell Sci,2012;125(Pt 14):3257-63. Click for abstract.
  5. Rao MV, Mohan P, Kumar A, Yuan A, Montagna L, Campbell J, Veeranna, Espreafico EM, Julien JP, Nixon RA. The Myosin Va head domain binds to the neurofilament-L rod and modulates Endoplasmic reticulum (ER) content and distribution within axons. PLoS ONE, 2011; 6(2):e17087. PMC3040190 Full text available:
  6. Dyakin VV, Chen Y, Branch CA, Veeranna, Yuan A, Rao MV, Kumar A, Peterhoff CM, Nixon RA. The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models. Neuroimage. 2010; 51(3):1098-1105. PMCID: PMC2862816 Full text available:
  7. Yuan A, Sasaki T, Rao MV, Kumar A, Kanumuri V, Dunlop DS, Liem RK and Nixon RA. Neurofilaments form a highly stable stationary cytoskeleton after reaching a critical level in axons. J Neurosci. 2009;29:11316-11329. Full text available:
  8. Yuan A, Kumar A, Peterhoff C, Duff K and Nixon RA. Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J Neurosci. 2008;28:1682-1687. Full text available:
  9. Yuan, A, Rao MV, Sasaki T, Chen Y, Kumar S, Veerranna, Liem RK, Eyer J, Peterson AC, Julien J-P and Nixon RA. a-Internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS. J Neurosci. 2006;26:10006-10019. Full text available:
  10. Yuan, A, Nixon RA, Rao MV. Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo.Neurosci. Lett. 2006;393:264-268. Click for abstract
  11. Rao, MV, Campbell J, Yuan A, Kumar A, Gotow T, Uchiyama Y, Nixon RA. The neurofilament middle molecular weight subunit carboxyl terminal tail domains are essential for the radial growth and cytoskeletal architecture of the axon but not for the regulation of rate of neurofilament transport. J Cell Biol. 2003;163:1021-1031. Full text available:
  12. Yuan A, Rao MV, Kumar A, Julien JP, Nixon RA. Neurofilament transport in vivo minimally requires hetero-oligomer formation. J Neurosci. 2003;23:9452-9458. Full text available:
  13. Rao, MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J. Cell Biol. 2002;158:681-693. Full text available:
  14. Rao, MV, Engle LJ, Mohan P, Yuan A, Qiu D, Cataldo, A, Hassinger L, Jacobsen S, Lee VM-Y, Andreadis A, Julien J-P, Bridgeman PC, Nixon RA. Binding of myosin Va to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. J. Cell Biol. 2002;159:279-290. Full text available:
  15. Bourke, GJ, El Alami W, Wilson SJ, Yuan A, Roobol A, Carden MJ. Slow axonal transport of the cytosolic chaperonin CCT with Hsc73 and actin in motor neurons. J. Neurosci. Res. 2002; 68:29-35. Click for abstract
  16. Yuan, A, Chia CP. Giant vacuoles observed in Dictyostelium discoideum. Cell Biol. Int. 2001;25:147-155. Click for abstract
  17. Yuan, A, Siu CH, Chia CP. Calcium requirement for efficient phagocytosis by Dictyostelium discoideum. Cell Calcium 2001;29:229-238. Click for abstract
  18. Yuan, A, Mills RG, Chia CP, Bray JJ. Tubulin and neurofilament proteins are transported differently in axons of chicken motoneurons. Cell Mol. Neurobiol. 2000;20:623-632. Click for abstract
  19. Yuan, A, Chia CP. Role of esterase gp70 and its influence on growth and development of Dictyostelium discoideum. Exp. Cell Res. 2000;261:336-347. Click for abstract
  20. Yuan, A, Mills RG, Bamburg JR, Bray JJ. Cotransport of glyceraldehyde-3-phosphate dehydrogenase and actin in axons of chicken motoneurons. Cell Mol. Neurobiol. 1999;19:733-744. Click for abstract
  21. Yuan, A, Chia CP. Co-loss of profilin I, II and cofilin with actin from maturing phagosomes in Dictyostelium discoideum. Protoplasma, 1999:209:214-225.
  22. Yuan, A, Pardy RL, Chia CP. Non-specific interactions alter lipopolysaccharide patterns and protein mobility on sodium dodecyl sulfate polyacrylamide gels. Electrophoresis. 1999;20:1946-1949. Click for abstract
  23. Yuan, A, Mills RG, Bamburg JR, Bray JJ. Axonal transport and distribution of cyclophilin A in chicken neurones. Brain Res. 1997;771:203-212. Click for abstract
  24. Mills, RG, Minamide LS, Yuan A, Bamburg JR, Bray JJ. Slow axonal transport of soluble actin with actin depolymerising factor, cofilin and profilin suggests actin moves in an unassembled form. J. Neurochem. 1996;67:1225-1234 Click for abstract
  25. Yuan A, Baird MA. Changes in the frequency and function of rat spleen dendritic cells occur with age. Aging: Immunol. & Infect Dis. 1994;5:121-132.

Reviews, Books, and Book Chapters

  1. Yuan A, Rao MV, Veeranna, Nixon RA. Neurofilaments at a glance. J Cell Sci. 2012;125(Pt 14):3257-63. Click for abstract
  2. Nixon RA, Yuan A (Eds.) Cytoskeleton of the Nervous System. New York: Springer Publication, 2011, 774p. ISBN 978-1-4419-6786-2.
  3. Yuan A, Nixon RA. Alpha-internexin: The fourth subunit of neurofilaments in the mature CNS. In: Cytoskeleton of the Nervous System, Vol 3; A. Yuan, R.A. Nixon (Eds.); Advances in Neurobiology, A. Lajtha (Ed.) New York: Springer Publication, 2011 pp.189-200 [Chapter 8]. ISBN-13: 978-1-4419-6786-2
  4. Yuan A, Nixon RA. Axonal transport mechanisms in cytoskeleton formation and regulation. In: Cytoskeleton of the Nervous System, Vol 3; A. Yuan, R.A. Nixon (Eds.); Advances in Neurobiology, A. Lajtha (Ed.) New York: Springer Publication, 2011 pp.503-528 [Chapter 21]. ISBN-13: 978-1-4419-6786-2
  5. Yuan A. Neurofilament protein partnership, export, transport, phosphorylation and neurodegeneration. In: New Research on Neurofilament Proteins; Arlen, R.K. (Ed.); New York: Nova Science Publishers, 2007 pp.53-79.

[last updated 11.24.14]