Research from Nixon and Nixon Lab Members Covered in Nature
The future of Alzheimer’s treatment, a featured article in the April 16, 2025 edition of Nature discusses the welcome arrival of drugs that clear away brain plaques but cautions that targeting amyloid alone might not be enough to halt the disease. The article covers research from Dr. Ralph Nixon and his researchers at the CDR who are credited with pioneering the theory, that is beginning to gain acceptance, that there could be an even earlier target for AD intervention: dysfunction of lysosomes, the cells’ waste-clearance machinery.