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Nixon Publishes Review in Nature Reviews Molecular Cell Biology

We are excited to announce that Dr. Ralph Nixon, with Dr. David Rubinsztein, has published a review paper titled, “Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases,” in the August 2024 issue of Nature Reviews Molecular Cell Biology.

As the title suggests, Nixon and Rubinsztein bring their expertise together to review the role of autophagy and lysosomes in neurodegenerative diseases such as Alzheimer disease, Parkinson disease and frontotemporal dementia. The authors also discuss the strong impact of cellular ageing on lysosomes and autophagy as a tipping point for the late-age emergence of related neurodegenerative disorders.

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