Nasca Lab Publishes in Biological Psychiatry: Global Open Science
Senior author Carla Nasca, first author Hope Kronman, members of the Nasca Lab and colleagues recently published an article titled, “Multidimensional Effects of Stress on Neuronal Exosome Levels and Simultaneous Transcriptomic Profiles.” This study investigates how chronic restraint stress impacts exosome levels and aims to pinpoint the key molecular factors that influences these changes during the stress response. The study provides a foundation for future studies of new forms of local and distant communication in stress neurobiology by demonstrating specific relationships between neuronal exosome levels assayed in plasma and the brain and providing new candidate targets for the normalization of exosome levels. The article appeared in the Biological Psychiatry Global Open Science Volume 5, Issue 1, January 2025 edition.